Experts say climate change linked to 10% rise in salmonella antibiotic resistance genes between 1940 and 2023
Andrew Gregory Health editorTue 26 May 2026 18.30 EDTShare
The climate crisis is accelerating a global increase in antibiotic resistance that poses a serious threat to human health, experts have said as figures show a rise in salmonella antibiotic resistant genes.
Antibiotic resistance is one of the fastest-growing threats to global health. It can affect people of any age in any country and already kills more than 1 million people a year, according to estimates.
Now a study, led by researchers from the UK, France, Australia, Switzerland and China, has revealed how climate change is linked to rising antibiotic resistance in salmonella, one of the world’s most common bacterial diseases.
Climate change is associated with a 10% global increase in salmonella antibiotic resistance genes between 1940 and 2023, according to the first-of-its-kind study, which has been published in the Lancet Planetary Health journal.
The main drivers of antibiotic resistance are still the misuse and overuse of antibiotics, which are used to treat infections. But the research suggested the problem is being worsened by climate change.
“The accumulated evidence suggests that climate change is an accelerating force behind the global spread of antimicrobial resistance,” the study authors wrote.
“Our findings provide supporting evidence that rising temperatures and altered precipitation patterns non-linearly amplify the abundance and dissemination of antimicrobial resistance genes in bacterial pathogens such as salmonella.
“These findings reinforce the idea that climate change alters microbial ecological stability and accelerates resistance evolution across human, animal, and environmental reservoirs.
“Urgent integration of climate change-mitigation policies, particularly those aligned with the Paris agreement – with enhanced antimicrobial stewardship and One Healthsurveillance – is essential to curtail the future burden of antimicrobial resistance.”
Antimicrobial resistance is mainly driven by the overuse and misuse of antibiotics, which allows resistant bacteria to survive and spread. However, rising temperatures and changing rainfall patterns can influence how bacteria survive, mutate and spread, potentially increasing the exchange of antibiotic resistance genes, the researchers said.
Previous studies have linked higher temperatures to greater levels of resistant bacteria, but until now global quantitative studies on the link have been limited.
The new study analysed the genomes of more than 480,000 salmonella samples from 139 countries collected between 1940 and 2023. Levels of antibiotic resistance genes were compared with changes in average temperature and rainfall over time.
Using a model to study the relationship, the researchers found that antibiotic resistance does not just increase steadily as temperatures rise, but that the number of resistance genes changes over time in a more complicated way depending on both temperature and rainfall.
This suggests that environmental changes can speed up how bacteria adapt to antibiotics, according to the researchers.
The study found that 82% of countries studied had increases in antibiotic resistance genes in salmonella. The strongest climate-associated increases were found to be in the Middle East and north Africa, followed by south Asia, and sub-Saharan Africa.
The study showed a link between climate change and antibiotic resistance genes in salmonella, but did not prove that climate change was directly causing the increase. However, the authors said their findings highlight the need to consider climate change when it comes to global efforts in tackling antibiotic resistance.
Urgent action, alongside responsible antibiotic use and improved disease surveillance, will be key to limiting the future spread of antibiotic resistance, they added.
Their study provided “robust evidence” that climate change is associated with a heightened risk of antibiotic resistance, they said.
“The findings emphasise that combining climate change-mitigation efforts and antibiotic stewardship, such as adhering to the low-emission scenarios, could effectively curb the dissemination of antimicrobial resistance genes and rise in global antimicrobial resistance.”
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